Macbeth - Act 5 Scene 1

Dunsinane. Ante-room in the castle.

Enter a Doctor of Physic and a Waiting-Gentlewoman

This scene begins with description of off-stage action, letting us know that time has passed. Macbeth has been in the field, presumably fighting against the rebels, and the Doctor and Gentlewoman have met twice before outside Lady Macbeth's chamber.

Doctor
I have two nights watched with you, but
can perceive no truth in your report. When
was it she last walked?

Gentlewoman
Since his Majesty went into the field, I have
seen her rise from her bed, throw her nightgown
upon her, unlock her closet, take forth paper,
fold it, write upon't, read it, afterwards seal it,
and again return to bed; yet all this while in a
most fast sleep.

Doctor
A great perturbation in nature, to receive at once
the benefit of sleep, and do the effects of
watching! In this slumbery agitation, besides her
walking and other actual performances, what, at any
time, have you heard her say?

Gentlewoman
That, sir, which I will not report after her.

Doctor
You may to me: and 'tis most meet you should.

Gentlewoman
Neither to you nor any one; having no witness to
confirm my speech.

A taper is a kind of candle, made of a long rope wick dipped in wax or pitch. It indicates that the action is indoors and in the dark of night, and the image of a single flickering flame in the darkness is a potent indication of the stage of Lady Macbeth's soul and sanity.

This is a telling detail as well, hinting that, in Macbeth's absence, Lady Macbeth has developed a fear of the dark. 

Enter LADY MACBETH, with a taper

Lo you, here she comes! This is her very guise;
and, upon my life, fast asleep. Observe her;
stand close.

Doctor
How came she by that light?

Gentlewoman
Why, it stood by her: she has light by her continually;
'tis her command.

Doctor
You see, her eyes are open.

Gentlewoman
Ay, but their sense is shut.

Doctor
What is it she does now? Look, how she rubs her hands.

Gentlewoman
It is an accustomed action with her, to seem thus
washing her hands: I have known her continue in
this a quarter of an hour.

Lady Macbeth's action here recalls Macbeth's lines in 2.2, and the image of indelible bloodstains, as well as metaphorical stains of mind and soul that can never be removed.

LADY MACBETH
Yet here's a spot.

Doctor
Hark! She speaks: I will set down what comes from
her, to satisfy my remembrance the more strongly.

Lady Macbeth's speeches conjure up snatches of her dialogue from earlier in the play. They may be delivered as they had been initially, or may be altered to indicate her current terror and distress.

LADY MACBETH
Out, damned spot! Out, I say! – One: two: why,
then, 'tis time to do't. – Hell is murky! – Fie, my
lord, fie! A soldier, and afeard? What need we
fear who knows it, when none can call our power to
account? – Yet who would have thought the old man
to have had so much blood in him.

Doctor
Do you mark that?

LADY MACBETH
The Thane of Fife had a wife: where is she now? –
What, will these hands ne'er be clean? – No more o'
that, my lord, no more o' that: you mar all with
this starting.

The Doctor's attention shifts here from Lady Macbeth's malady to a more pragmatic concern for himself and the Gentlewoman: having heard an apparent confession, they may well be in danger themselves.

Doctor
Go to, go to; you have known what you should not.

Gentlewoman
She has spoke what she should not, I am sure of
that: heaven knows what she has known.

LADY MACBETH
Here's the smell of the blood still: all the
perfumes of Arabia will not sweeten this little
hand. Oh, oh, oh!

Doctor
What a sigh is there! The heart is sorely charged.

Gentlewoman
I would not have such a heart in my bosom for the
dignity of the whole body.

Doctor
Well, well, well –

Gentlewoman
Pray God it be, sir.

The Doctor identifies Lady Macbeth's condition as a mental or spiritual illness, rather than a physical one. His comment raises the possibility of her death, as well as suggesting some hope for her soul.

Doctor
This disease is beyond my practise: yet I have known
those which have walked in their sleep who have died
holily in their beds.

LADY MACBETH
Wash your hands, put on your nightgown; look not so
pale. – I tell you yet again, Banquo's buried; he
cannot come out on's grave.

Doctor
Even so?

The repetitions in these lines indicate a rising urgency. These lines become quite ominous when we consider that these are to become Lady Macbeth's last words.

LADY MACBETH
To bed, to bed! There's knocking at the gate:
come, come, come, come, give me your hand. What's
done cannot be undone. – To bed, to bed, to bed!

Exit

Doctor
Will she go now to bed?

Gentlewoman
Directly.

The Doctor's instructions to the Gentlewoman suggest that Lady Macbeth may be suicidal, a detail which resurfaces at the end of 5.8.

Doctor
Foul whisperings are abroad: unnatural deeds
Do breed unnatural troubles; infected minds
To their deaf pillows will discharge their secrets.
More needs she the divine than the physician.
God, God forgive us all! Look after her;
Remove from her the means of all annoyance,
And still keep eyes upon her. So, good night.
My mind she has mated, and amazed my sight.
I think, but dare not speak.

Gentlewoman
Good night, good Doctor.

Exeunt